Senior Manager, Biopharma Partnerships | Neuro
FYR
Sales & Business Development
United States
Posted on Apr 12, 2026
At Two Bear Capital we believe in partnering with our founders to build the best companies possible. We look forward to working with you for FYR Bio's new Business Development Lead.
Business Development Lead / Senior Manager, Biopharma Partnerships (Neuro)
Remote | Contract / Fractional (Preferred) or Full-Time
Overview
We are seeking a senior, commercially driven Business Development professional to originate, structure, and help close strategic partnerships with biopharma companies, with a focus on neuro-oncology and neurodegenerative disease.
This is a high-impact “hunter” role focused on building relationships with key decision-makers and driving large, multi-phase engagements. While early engagements may begin with smaller studies, the core objective is to establish long-term, high-value partnerships.
We are open to structuring this role as fractional/contract or full-time, with a preference for a contractor model to start.
Role Focus
- Build and convert a pipeline of strategic biopharma opportunities
- Engage senior stakeholders across: Business Development, Clinical Development, Medical Affairs, Strategy and Innovation
- Drive high-value deal creation, not high-volume outreach
- Help shape how engagements are structured, priced, and expanded over time
Required Experience
- 7–15+ years in business development, partnerships, or commercial roles within: Biopharma, CROs, life sciences services, or consulting
- Proven track record of: Closing or materially contributing to large, complex B2B deals, selling into pharma/biotech organizations and navigating multi-stakeholder environments
- Strong understanding of drug development and stakeholder landscape
Preferred Profile
- Existing network within neuro-oncology, CNS, or related therapeutic areas
- Experience structuring multi-phase or strategic partnerships
- Strong negotiation and deal-making capabilities
- Entrepreneurial mindset; comfortable operating in an early-stage environment
- Ability to operate independently while collaborating closely with leadership
Key Responsibilities:
Strategic Pipeline Development
- Identify and prioritize target pharma/biotech accounts within neuro/CNS
- Leverage existing network and targeted outreach to access decision-makers
- Relationship development: build trust with senior stakeholders across target organizations and establish credibility within the neuro-focused biopharma ecosystem
Deal Origination & Structuring
- Lead early-stage conversations and opportunity shaping
- Collaborate with internal leadership to define scope, pricing, and long-term
- partnership opportunities
Deal Progression & Closing Support
- Drive opportunities from initial engagement through proposal and negotiation
- Navigate complex stakeholder and procurement environments
Commercial Strategy Input
- Provide feedback on positioning, messaging, and market dynamics
- Help refine go-to-market approach based on real-world interactions
What Success Looks Like
- Development of a high-quality pipeline within target neuro-focused accounts
- Access to senior decision-makers across pharma/biotech organizations
- Progression and closure of large ($250K–$1M+) strategic engagements
- Establishment of long-term partnerships and expansion opportunities
Preferred Profile
- Existing network within neuro-oncology, CNS, or related therapeutic areas
- Experience structuring multi-phase or strategic partnerships
- Strong negotiation and deal-making capabilities
- Entrepreneurial mindset; comfortable operating in an early-stage environment
- Ability to operate independently while collaborating closely with leadership
Why Join
- Opportunity to directly influence company trajectory through high-value partnerships
- High ownership and visibility with leadership
- Flexibility in engagement structure (contract or full-time)
- Ability to shape the commercial strategy in a growing organization
- Work at the intersection of innovation and neuroscience